Complement C5a des-Arg; Human

Code: 204902-30UG D2-231

General description

Native, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human...


read more

Your Price
€651.00 EACH
€800.73 inc. VAT

General description

Native, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human plasma or serum, it is rapidly converted to C5a des-Arg upon removal of the C-terminal arginine by the endogenous serum carboxypeptidase N. Unlike the C3a des-Arg peptide, C5a des-Arg retains significant levels of its biological activities. Thus, C5a des-Arg has been shown to exhibit inflammatory cell chemotaxis, smooth muscle contraction, and leukotriene release from guinea pig lung.

Native, human des-Arg C5a complement component. Single chain glycopeptide composed of 73 amino acids. Once the C5a glycopeptide has been produced in human plasma or serum, it is rapidly converted to C5a des-Arg upon removal of the C-terminal arginine by the endogenous serum carboxypeptidase N. Unlike the C3a des-Arg peptide, C5a des-Arg retains significant levels of its biological activities. Thus, C5a-des-Arg has been shown to exhibit inflammatory cell chemotaxis, smooth muscle contraction, and leukotriene release reactions from guinea pig lung.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Webster, R.O., et al. 1980. Immunopharmacology 1, 201.McCarthy, K. and Henson, P.M. 1979. J. Immunol. 123, 2511.

Packaging

30 µg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Physical form

In 120 mM NaCl, 10 mM HEPES, pH 7.2.

Preparation Note

Prepared from plasma of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Warning

Toxicity: Standard Handling (A)

assay≥90% (SDS-PAGE)
formliquid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inwet ice
storage conditionavoid repeated freeze/thaw cycles, OK to freeze
storage temp.−70°C
This product has met the following criteria to qualify for the following awards:



PROCEED TO CHECKOUT

HAVE AN ACCOUNT? LOGIN


GUEST CHECKOUT

Proceed as a guest. You will have the option to register to access exclusive pricing and stock availability features after checkout.